Georgetown Researchers Uncover Key Differences in Bacterial Protein Regulation
February 11th, 2025
A new study led by Dr. Rodrigo Maillard at Georgetown University, “Identifying Allosteric Hotspots in Mycobacterium tuberculosis cAMP Receptor Protein through Structural Homology,” published in Biochemistry sheds light on how bacteria regulate their genes, challenging long-held assumptions about protein behavior. Published in Biochemistry, the research compares how two bacterial species—Escherichia coli and Mycobacterium tuberculosis—use a signaling molecule called cyclic AMP (cAMP) to control important cellular functions.…
![A, B} Spatial map of dynamical heterogeneities obtained in simulations of model colloidal gels. [1,2] C) 3D rendering of a confocal microscopy image of a part of a colloidal gel taken in the Blair lab](https://softmatter.georgetown.edu/wp-content/uploads/sites/279/2023/01/1-24-grant-article.png "A, B} Spatial map of dynamical heterogeneities obtained in simulations of model colloidal gels. [1,2] C) 3D rendering of a confocal microscopy image of a part of a colloidal gel taken in the Blair lab")
